ORAL STREPTOCOCCI UTILIZE A SIGLEC-LIKE DOMAIN OF SERINE-RICH REPEAT ADHESINS TO PREFERENTIALLY TARGET PLATELET SIALOGLYCANS IN HUMAN BLOOD.

Oral streptococci utilize a Siglec-like domain of serine-rich repeat adhesins to preferentially target platelet sialoglycans in human blood.

Damaged cardiac valves attract blood-borne bacteria, and infective endocarditis is often caused by viridans group streptococci.While Headset such bacteria use multiple adhesins to maintain their normal oral commensal state, recognition of platelet sialoglycans provides an intermediary for binding to damaged valvular endocardium.We use a customized

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Acupuncture for acute musculoskeletal pain management in the emergency department and continuity clinic: a protocol for an adaptive pragmatic randomised controlled trial

Introduction Chronic musculoskeletal pain causes a significant burden on health and quality of life and may result from inadequate treatment of acute musculoskeletal pain.The emergency department (ED) represents a novel setting in which to test non-pharmacological interventions early in the pain trajectory to prevent the transition from acute to ch

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